Isoquinolin-5-ylboronic acid hydrochloride
Isoquinolin-5-ylboronic acid hydrochloride
CAS: 1256345-46-6
Molecular Formula: C9H9BClNO2
Isoquinolin-5-ylboronic acid hydrochloride - Names and Identifiers
| Name | Isoquinolin-5-ylboronic acid hydrochloride |
| Synonyms | Isoquinolin-5-ylboronic acid hydrochloride isoquinolin-5-yl-5-boronic acid hydrochloride |
| CAS | 1256345-46-6 |
Isoquinolin-5-ylboronic acid hydrochloride - Physico-chemical Properties
| Molecular Formula | C9H9BClNO2 |
| Molar Mass | 209.43726 |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | IRRITANT |
| MDL | MFCD08235064 |
Isoquinolin-5-ylboronic acid hydrochloride - Introduction
Isoquinolin-5-ylboronic acid hydrochloride(Isoquinolin-5-ylboronic acid hydrochloride) is a compound with the chemical formula C9H9BClNO2.
Nature:
Isoquinolin-5-ylboronic acid hydrochloride is a solid powder, soluble in water and some organic solvents. It is oxidizing and is susceptible to oxidation and discoloration in the air.
Use:
As a reagent for organic synthesis, it is commonly used in metal-catalyzed reactions. It can be used as a ligand under acid or alkaline conditions to participate in various organic synthesis reactions, such as Suzuki coupling, Stille coupling and Buchwald-Hartwig reaction. It also has certain applications in drug development and can be used as an intermediate for the synthesis of drug molecules.
Preparation Method:
Generally, Isoquinolin-5-ylboronic acid hydrochloride can be prepared by the reaction of isoquinoline-5-boronic acid (Isoquinolin-5-boronic acid) and hydrochloric acid. First, isoquinoline-5-boronic acid is added to hydrochloric acid, reacted at an appropriate temperature for a certain period of time, and then the product is obtained by filtration and washing.
Safety Information:
The specific safety information hydrochloride by Isoquinolin-5-ylboronic acid needs to be determined on a case-by-case basis, including its purity and use. However, in general, good laboratory safety practices need to be followed for the handling and handling of chemicals. Personal protective equipment such as laboratory gloves, eye and respiratory protection should be worn during use.
Nature:
Isoquinolin-5-ylboronic acid hydrochloride is a solid powder, soluble in water and some organic solvents. It is oxidizing and is susceptible to oxidation and discoloration in the air.
Use:
As a reagent for organic synthesis, it is commonly used in metal-catalyzed reactions. It can be used as a ligand under acid or alkaline conditions to participate in various organic synthesis reactions, such as Suzuki coupling, Stille coupling and Buchwald-Hartwig reaction. It also has certain applications in drug development and can be used as an intermediate for the synthesis of drug molecules.
Preparation Method:
Generally, Isoquinolin-5-ylboronic acid hydrochloride can be prepared by the reaction of isoquinoline-5-boronic acid (Isoquinolin-5-boronic acid) and hydrochloric acid. First, isoquinoline-5-boronic acid is added to hydrochloric acid, reacted at an appropriate temperature for a certain period of time, and then the product is obtained by filtration and washing.
Safety Information:
The specific safety information hydrochloride by Isoquinolin-5-ylboronic acid needs to be determined on a case-by-case basis, including its purity and use. However, in general, good laboratory safety practices need to be followed for the handling and handling of chemicals. Personal protective equipment such as laboratory gloves, eye and respiratory protection should be worn during use.
Last Update：2024-04-09 21:01:54
